LAPD criminalist Gregory Matheson dominated the day with direct examination testimony on evidence documentation, serology methods, degradation, fingernail scrapings, blood drop 49, and the volume estimate for Simpson's reference sample. He testified that drop 49 could only have been donated by OJ Simpson, excluding Nicole Brown Simpson and Ron Goldman, and that the fingernail blood was more likely than not Nicole Brown Simpson's. Blasier's cross-examination focused on lab training, certification, accreditation, and a meeting Matheson, Kestler, and Yamauchi had with Mazzola during her testimony to discuss style and potential questions.

• Matheson testified that his June 29 visual estimate of 2ml was far off; on September 21, he determined approximately 3.8ml of blood was present in the vial together with the centrifuge tube contained in the package
• Blood drop 49 from Bundy crime scene matches only OJ Simpson and excludes both victims
• Defense argued that Item 118, a knife found near Simpson's estate, tested EAP type B like the victims' nail scrapings; Judge Ito ordered the knife and its documentation produced for review
• Matheson confirmed that a hair was found inside item 6's control bindle on February 27 that was not present when the item was sent out on February 17
• Cross-examination disclosed that Matheson, lab director Kestler, and Yamauchi met with Mazzola during her testimony to discuss style and potential questions