The defense systematically dismantled LAPD's evidence handling practices through testimony from multiple crime scene personnel and detectives. Witnesses acknowledged unsealed blood specimens, unrefrigerated storage in hot trucks, uninitialed evidence bindles, and approximately 1.5 cc of unaccounted blood from Simpson's reference vial. Detective Vannatter admitted chain of custody failures; criminalist Mazzola testified she was a trainee with only six months experience; nurse Peratis was caught changing his sworn testimony about blood volume drawn; and Detective Lange was grilled on Fuhrman's suspicious role in evidence collection.

• Detective Vannatter conceded he never sealed Simpson's blood specimen envelope, leaving it unsealed in his possession for roughly three hours
• Criminalist Andrea Mazzola, a self-described crime scene trainee with only six months experience, admitted she failed to change gloves between collecting evidence and never photographed or documented critical procedures
• Nurse Thano Peratis changed sworn testimony about blood volume drawn from Simpson—originally 8 cc at grand jury and preliminary hearing, later revised to 6-6.5 cc after hearing Cochran's opening statement about missing blood
• LAPD stored wet blood swatches unrefrigerated in a hot crime-scene truck for up to ten hours, then dried them in an unlocked cabinet alongside Simpson's reference blood vial with no chain of custody documentation
• Serologist Matheson acknowledged approximately 1.5 cc of blood was unaccounted for between collection and toxicology testing of Simpson's reference sample
• Detective Tom Lange was challenged on crime scene procedures and Fuhrman's unauthorized and suspicious role in evidence collection at Rockingham