Dr. Cotton, with regard to these five probes, do you need all five probes run on the same people in your database to create these estimates of frequencies of these various characteristics?
You do not need to have all five probes on all the people in order to create these estimates. For statistical purposes of independence, when tests are done for independence for RFLP testing, those tests are generally done for pairs of loci. So you need pairs of people that have been done on two at a minimum, and this database has those pairs. It isn't that more information can't be gained if you have people across all five loci, but we do have enough information as a database exists for those tests of independence to be done.
KEY QUOTEHas or have your five probes been looked at for purposes of determining if they are independent from one another?
All right. The fact that it's been published isn't hearsay. What it says is hearsay. Proceed.
KEY QUOTEAnd was that publication an examination of your database and a determination of independence of these five probes?
Has there been any publication to your knowledge demonstrating that your five genetic markers are not independent of one another?
You do not need to have all five probes on all the people in order to create these estimates. For statistical purposes of independence, when tests are done for independence for RFLP testing, those tests are generally done for pairs of loci.
No, there has not.
The fact that it's been published isn't hearsay. What it says is hearsay. Proceed.