First of all, Dr. Cotton, if you have 21 genotypes and you know which alleles are not present, you could take all the possible heterozygous and homozygous type frequencies for those alleles that are not present and add up the sum of those frequencies, could you?
Yes, the ones that could be present plus the ones that couldn't be present equal the total.
Exactly. So if you start out with a hundred percent and you subtract the genotype frequencies which could not be present--which could not have contributed to that mixture and you subtract that from a hundred percent, you are left with some number, right?
That number is the same whether you have two contributors, three contributors or ten contributors; isn't that right?
Sometimes I have to take a piece of paper and work on them and then answer that question. I'm not sure that it is wrong, but I'm not sure that it is right.
KEY QUOTEOkay. And just getting back to one other point, other than the NRC report which says that you indeed have to aggregate this data, you are aware of no authority to the contrary?
I'm not so sure that that is right.
Are you sure that it is wrong?
That is real helpful.
Sometimes I have to take a piece of paper and work on them and then answer that question. I'm not sure that it is wrong, but I'm not sure that it is right.